Nouvelle publication de l'équipe
Diallel panel reveals a significant impact of low-frequency genetic variants on gene expression variation in yeast. Andreas Tsouris, Gauthier Brach, Anne Friedrich, Jing Hou, Joseph Schacherer. Mol Syst Biol. 2024. doi:10.1038/s44320-024-00021-0 Unraveling the genetic sources of gene expression…
Nouvelle publication dans NAR
Translation variation across genetic backgrounds reveals a post-transcriptional buffering signature in yeast. Elie M Teyssonniere, Yuichi Shichino, Mari Mito, Anne Friedrich, Shintaro Iwasaki, Joseph Schacherer. Nucleic Acids Research. 2024. doi:10.1093/nar/gkae030 Gene expression is known to…
Nouvelle publication dans PLos Genetics
Species-wide survey of the expressivity and complexity spectrum of traits in yeast. Andreas Tsouris, Téo Fournier, Anne Friedrich, Jing Hou, Maitreya J. Dunham, Joseph Schacherer. Assessing the complexity and expressivity of traits at the species level is an essential first step to better dissect…
Nouvelle publication dans Cell Genomics
Non-additive genetic components contribute significantly to population-wide gene expression variation. Andreas Tsouris, Gauthier Brach, Joseph Schacherer, Jing Hou. Gene expression variation, an essential step between genotype and phenotype, is collectively controlled by local (cis) and distant (tr…
Nouvelle publication dans Nature Genetics
Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae. Samuel O’Donnell, Jia-Xing Yue, Omar Abou Saada, Nicolas Agier, Claudia Caradec, Thomas Cokelaer, Matteo De Chiara, Stéphane Delmas, Fabien Dutreux, Téo Fournier, Anne Friedrich,…
Nouvelle publication en collabration
Copy number variation alters local and global mutational tolerance. Grace Avecilla, Pieter Spealman, Julia Matthews, Elodie Caudal, Joseph Schacherer, David Gresham. Copy number variants (CNVs), duplications and deletions of genomic sequences, contribute to evolutionary adaptation but can also…
Nouvelle publication dans G3
Impact of the acquired subgenome on the transcriptional landscape in Brettanomyces bruxellensis allopolyploids. Arthur Jallet, Anne Friedrich, Joseph Schacherer. G3 Genes|Genomes|Genetics. 2023. doi:10.1093/g3journal/jkad115 Gene expression variation can provide an overview of the changes in…
Nouvelle publication dans Genome Biology and Evolution
Contrasting genomic evolution between domesticated and wild Kluyveromyces lactis yeast populations. Anne Friedrich, Jean-Sébastien Gounot, Andreas Tsouris, Claudine Bleykasten, Kelle Freel, Claudia Caradec, Joseph Schacherer. Genome Biology and Evolution. 2023. doi:10.1093/gbe/evad004 The process…
Nouvelle publication dans PLoS Genetics
Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii. Fabien Dutreux, Abhishek Dutta, Emilien Peltier, Sabrina Bibi-Triki, Anne Friedrich, Bertrand Llorente, Joseph Schacherer. PLoS Genet. 2023. doi:10.1371/journal.pgen.1010592 Meiotic recombination…
Nouvelle publication dans Molecular Biology and Evolution
Loss of heterozygosity spectrum depends on ploidy level in natural yeast populations. Abhishek Dutta, Fabien Dutreux, Joseph Schacherer. Molecular Biology and Evolution. 2022. doi:10.1093/molbev/msac214 The appearance of genomic variations such as loss of heterozygosity (LOH) has a significant…