Species-wide survey of the expressivity and complexity spectrum of traits in yeast. Andreas Tsouris, Téo Fournier, Anne Friedrich, Jing Hou, Maitreya J. Dunham, Joseph Schacherer. Assessing the complexity and expressivity of traits at the species level is an essential first step to better dissect the genotype-phenotype relationship. As trait…
nPhase: an accurate and contiguous phasing method for polyploids
The dynamics of loss of heterozygosity events in genomes. Abhishek Dutta, Joseph Schacherer. Genomic instability is a hallmark of tumorigenesis, yet…
Species-wide survey of the expressivity and complexity spectrum of traits in yeast. Andreas Tsouris, Téo Fournier, Anne Friedrich, Jing Hou, Maitreya…
The Laboratory of Excellence (LabEx) MitoCross announces the call for applications for two junior chairs in the field of research on mitochondria.
nPhase: an accurate and contiguous phasing method for polyploids
Nouvelle publication de l'équipe: Pervasive phenotypic impact of a large non-recombining introgressed region in yeast.
Nouvelle publication de l'équipe : High complexity and degree of genetic variation in Brettanomyces bruxellensis population.
Extensive impact of low-frequency variants on the phenotypic landscape at population-scale.
The induction of HAD-like phosphatases by multiple signaling pathways confers resistance to the metabolic inhibitor 2-deoxyglucose. Science Signaling…
Nouvelle publication en collaboration avec Philippe Marullo : Quantitative Trait Nucleotides impacting the technological performances of industrial…
Nouvelle publication en collaboration avec l'équipe d'Eric Alani (Cornell University) : Incompatibilities in mismatch repair genes MLH1-PMS1…
Les 1011 génomes de S. cerevisiae sont publiés dans Nature : Genome evolution across 1,011 Saccharomyces cerevisiae isolates
Deux nouvelles publications de l'équipe et en collaboration : Genetic backgrounds and hidden trait complexity in natural populations. Identification…
Quatre nouvelles publications de l'équipe et en collaboration : Variation of the meiotic recombination landscape and properties over a broad…
Une nouvelle publication en collaboration avec Eric Alani : Mismatch Repair Incompatibilities in Diverse Yeast Populations.
Nouvelle publication en collaboration avec le Génoscope : de novo assembly and population genomic survey of natural yeast isolates with the Oxford…
Natural proteome diversity links aneuploidy tolerance to protein turnover. Julia Muenzner, Pauline Trébulle, Federica Agostini, Henrik Zauber,…
Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast. Élodie Caudal, Victor Loegler, Fabien Dutreux,…
Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast. Elie M Teyssonnière,…
Absence of chromosome axis protein recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachancea kluyveri. Sylvain…
Diallel panel reveals a significant impact of low-frequency genetic variants on gene expression variation in yeast. Andreas Tsouris, Gauthier Brach,…
Translation variation across genetic backgrounds reveals a post-transcriptional buffering signature in yeast. Elie M Teyssonniere, Yuichi Shichino,…
Non-additive genetic components contribute significantly to population-wide gene expression variation. Andreas Tsouris, Gauthier Brach, Joseph…
Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae. Samuel O’Donnell, Jia-Xing…
Copy number variation alters local and global mutational tolerance. Grace Avecilla, Pieter Spealman, Julia Matthews, Elodie Caudal, Joseph Schacherer,…
Impact of the acquired subgenome on the transcriptional landscape in Brettanomyces bruxellensis allopolyploids. Arthur Jallet, Anne Friedrich, Joseph…
Contrasting genomic evolution between domesticated and wild Kluyveromyces lactis yeast populations. Anne Friedrich, Jean-Sébastien Gounot, Andreas…
Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii. Fabien Dutreux, Abhishek Dutta, Emilien Peltier,…
Loss of heterozygosity spectrum depends on ploidy level in natural yeast populations. Abhishek Dutta, Fabien Dutreux, Joseph Schacherer. Molecular…
Loss-of-function mutation survey revealed that genes with background-dependent fitness are rare and functionally related in yeast. Elodie Caudal, Anne…
Extensive simulations assess the performance of genome-wide association mapping in various Saccharomyces cerevisiae subpopulations. Jackson Peter,…
RNA interference (RNAi) as a tool for high-resolution phenotypic screening of the pathogenic yeast Candida glabrata. Andreas Tsouris, Joseph…
