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GMGM

New review article on LOH dynamics

The dynamics of loss of heterozygosity events in genomes. Abhishek Dutta, Joseph Schacherer. Genomic instability is a hallmark of tumorigenesis, yet…

New publication in PLos Genetics

Species-wide survey of the expressivity and complexity spectrum of traits in yeast. Andreas Tsouris, Téo Fournier, Anne Friedrich, Jing Hou, Maitreya…

New publication in Genome Biology

nPhase: an accurate and contiguous phasing method for polyploids

Equipe Variation intra-spécifique et évolution des génomes

Nouvelle publication de l'équipe: Pervasive phenotypic impact of a large non-recombining introgressed region in yeast.

Equipe Variation intra-spécifique et évolution des génomes

Nouvelle publication de l'équipe : High complexity and degree of genetic variation in Brettanomyces bruxellensis population.

Un nouvel article de l’équipe Variation intra-spécifique et évolution des génomes dans la revue eLife

Extensive impact of low-frequency variants on the phenotypic landscape at population-scale.

Trois publications en collaboration avec l'équipe Variation intra-spécifique et évolution des génomes

The induction of HAD-like phosphatases by multiple signaling pathways confers resistance to the metabolic inhibitor 2-deoxyglucose. Science Signaling…

Equipe Variation intra-spécifique et évolution des génomes

Nouvelle publication en collaboration avec Philippe Marullo : Quantitative Trait Nucleotides impacting the technological performances of…

Equipe Variation intra-spécifique et évolution des génomes

Nouvelle publication en collaboration avec l'équipe d'Eric Alani (Cornell University) : Incompatibilities in mismatch repair genes MLH1-PMS1…

Equipe Variation intra-spécifique et évolution des génomes

Les 1011 génomes de S. cerevisiae sont publiés dans Nature : Genome evolution across 1,011 Saccharomyces cerevisiae isolates

Equipe Variation intra-spécifique et évolution des génomes

Deux nouvelles publications de l'équipe et en collaboration : Genetic backgrounds and hidden trait complexity in natural populations. Identification…

Equipe Variation intra-spécifique et évolution des génomes

Quatre nouvelles publications de l'équipe et en collaboration : Variation of the meiotic recombination landscape and properties over a broad…

Equipe Variation intra-spécifique et évolution des génomes

Une nouvelle publication en collaboration avec Eric Alani : Mismatch Repair Incompatibilities in Diverse Yeast Populations.

Equipe Variation intra-spécifique et évolution des génomes

Nouvelle publication en collaboration avec le Génoscope : de novo assembly and population genomic survey of natural yeast isolates with the Oxford…

Equipe Variation intra-spécifique et évolution des génomes

Nouvelle publication de l'équipe dans Mol Biol Evol : Fitness trade-offs lead to suppressor tolerance in yeast.

Equipe Variation intra-spécifique et évolution des génomes

Nouvelle publication de l’équipe dans Cell Reports : The hidden complexity of mendelian traits across natural yeast populations.

Publications

New publication in collaboration

Natural proteome diversity links aneuploidy tolerance to protein turnover. Julia Muenzner, Pauline Trébulle, Federica Agostini, Henrik Zauber,…

New publication in Nature Genetics

Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast. Élodie Caudal, Victor Loegler, Fabien Dutreux,…

New publication in PNAS

Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast. Elie M Teyssonnière,…

New publication in collaboration

Absence of chromosome axis protein recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachancea kluyveri. Sylvain…

New publication of the team

Diallel panel reveals a significant impact of low-frequency genetic variants on gene expression variation in yeast. Andreas Tsouris, Gauthier Brach,…

New publication in NAR

Translation variation across genetic backgrounds reveals a post-transcriptional buffering signature in yeast. Elie M Teyssonniere, Yuichi Shichino,…

New publication in Cell Genomics

Non-additive genetic components contribute significantly to population-wide gene expression variation. Andreas Tsouris, Gauthier Brach, Joseph…

New publication in Nature Genetics

Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae. Samuel O’Donnell, Jia-Xing…

New publication in collabration

Copy number variation alters local and global mutational tolerance. Grace Avecilla, Pieter Spealman, Julia Matthews, Elodie Caudal, Joseph Schacherer,…

New publication in G3

Impact of the acquired subgenome on the transcriptional landscape in Brettanomyces bruxellensis allopolyploids. Arthur Jallet, Anne Friedrich, Joseph…

New publication in Genome Biology and Evolution

Contrasting genomic evolution between domesticated and wild Kluyveromyces lactis yeast populations. Anne Friedrich, Jean-Sébastien Gounot, Andreas…

New publication in PLoS Genetics

Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii. Fabien Dutreux, Abhishek Dutta, Emilien Peltier,…

New publication in Molecular Biology and Evolution

Loss of heterozygosity spectrum depends on ploidy level in natural yeast populations. Abhishek Dutta, Fabien Dutreux, Joseph Schacherer. Molecular…

New publication in PNAS

Loss-of-function mutation survey revealed that genes with background-dependent fitness are rare and functionally related in yeast. Elodie Caudal, Anne…

New publication

Extensive simulations assess the performance of genome-wide association mapping in various Saccharomyces cerevisiae subpopulations. Jackson Peter,…

Book chapter

RNA interference (RNAi) as a tool for high-resolution phenotypic screening of the pathogenic yeast Candida glabrata. Andreas Tsouris, Joseph…

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